Parkinson's disease and Alzheimer disease: environmental risk factors
نویسندگان
چکیده
منابع مشابه
Environmental and familial risk factors of Parkinsons disease: case-control study.
BACKGROUND While the cause of Parkinson's disease (PD) remains unknown, evidence suggests certain environmental factors, such as well water drinking, herbicides, pesticides exposure and neurotoxins, may trigger the chain of oxidative reactions culminating in the death of dopaminergic neurons in substantia nigra to cause Parkinsonism. To investigate the possible impact of environmental risk fact...
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The global prevalence of dementia is as high as 24 million, and has been predicted to quadruple by the year 2050. In the US alone, Alzheimer disease (AD) - the most frequent cause of dementia characterized by a progressive decline in cognitive function in particular the memory domain - causes estimated health-care costs of $ 172 billion per year. Key neuropathological hallmarks of the AD brain ...
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Objectives The current study examines the features of the physical environment affecting environmental perception and tries to explain paradigm of architecture based on the neuropsychological features. This paper investigates the relationship between the two aspects of the physical and neuropsychological environment in the patients with dementia Alzheimer’s type in order to meet the needs of th...
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Alzheimer disease and vascular cognitive impairment are important causes of cognitive decline in the elderly. It has now been shown that vascular risk factors have measurable negative effects on the brain and are associated with cognitive impairment. We review vascular factors that might be responsible to cognitive decline in Alzheimer disease and vascular cognitive impairment and the correspon...
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The vast majority of Parkinson’s disease (PD) is etiologically multifactorial, with important contributions from both genetic and environmental determinants. Very few cases of PD can be attributed to single gene disorders (1–5). For PD without single gene Mendelian inheritance, relative risks as high as 14 for first-degree relatives of PD cases have been reported (6), but most studies have foun...
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ژورنال
عنوان ژورنال: Neurología (English Edition)
سال: 2014
ISSN: 2173-5808
DOI: 10.1016/j.nrleng.2012.04.022